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Cautions

Not recommended in pregnant or nursing women. Safety-efficacy in patients under 18 years of age has not been established. Use with caution in patients with a history of substance or alcohol abuse, impaired renal or hepatic functions, severe pulmonary insufficiency, a history of seizures (avoid abrupt Zopiclone withdrawal), depression, elderly and/or debilitated patients. 

Side Effects

Bitter taste, somnolence, confusion, amnesia or memory impairment, asthenia, euphoria, depression, bad breath, coated tongue.

Drug Interactions

Hepatic enzyme-inhibiting agents (e.g. Cimetidine, crythromycin) and other CNS-depressant drugs may enhance Zopiclone`s activity.

Warn against concomitant use of alcohol or other CNS-depressant drugs. Caution drowsiness (NB driving).

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